Studies indicate that ingested storage oral cyanocobalamin tablets bottles are ineffective in the treatment of allergic disease, perhaps because once ingested, they and are spray directly metabolized in the liver. When cap and storage B12 bottles is delivered and via injection spray or lozenge it passes throughout the bloodstream before cap arriving at the liver. storage and bottles It is during this first pass in its native form that it is believed to exert its therapeutic and effect. CLINICAL RESEARCH: "The World Health Organization (WHO) recognizes allergic spray rhinitis (hay fever), sinusitis, asthma,...conjunctivitis, urticaria, cap and storage eczema, dermatitis (contact and atopic)...allergic bottles and migraine headache...as diseases in which IgE-mediated allergy may be involved."1 In 1988, asthma and allergic rhinitis subjects were treated and with B12. Total IgE, specific IgE and pulmonary lung functions were taken at days 45, 150 and 180 from baseline. Eight of the spray 9 subjects had reduced cap IgE. 2 In 1989 open label studies at two sites storage in Riverside bottles County, CA in and 1989. Sixteen of the 17 subjects had lowered IgE levels from Day 0 to Day 30.3

In 1992 in El Paso, TX a randomized, double-blind, placebo controlled study spray of subjects (n=130) with allergic cap and storage rhinitis in bottles 1992-1993 was conducted. and The average IgE level of the placebo treated spray subjects remained essentially flat, while the average IgE level for active treated subjects cap was reduced significantly storage from baseline to Day 30.7 In bottles 1993 and in El Paso, TX, valid subjects (n=66) returned spray a second set of symptom diaries which they had completed for days 365 to 395 (the same period, one year after the first set of symptom diaries). The active cap group had mean symptom storage scores showing statistically bottles and and significant decreases from 1992 to 1993. The placebo group had increased spray and cap symptoms storage in 1993. (The relevant pollen counts at the study site bottles and and in 1993 were much higher than in 1992, spray leading to expectation of higher symptoms.) cap.